An off-key Liverpool were frustrated for a second successive game by struggling opponents as they were held to a 0-0 Premier League draw at Newcastle United on Wednesday.
Juventus substitute Cristiano Ronaldo was denied a stoppage-time winner by VAR as Udinese came from two goals down to snatch a 2-2 draw in their thrilling Serie A season opener on Sunday.
Lopetegui blends youth and experience in Spain World Cup squad
Images from football matches played in La Liga and Serie A in Spain and Italy on Wednesday.
Ballon d'Or winner Cristiano Ronaldo scored the opening goal as 10-man Real Madrid beat Osasuna 2-0 on Wednesday to qualify for the King's Cup quarter-finals 4-0 on aggregate.
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Images from the English Premier League matches played on Saturday.
Images from the FIFA World Cup qualifiers matches.
Atletico Madrid suffered a first defeat in 13 games in all competitions as they lost 1-0 at home to Villarreal on Tuesday after a late strike from substitute Roberto Soriano.
Cristiano Ronaldo and Gareth Bale both scored as Real Madrid staged a remarkable late comeback from two goals down to win 3-2 at Villarreal and stay top of La Liga.
In other European football action Real Madrid were left frustrated after a goalless draw against Athletic Bilbao in their La Liga match on Sunday.
Cristiano Ronaldo scored his 400th goal for Real Madrid as Zinedine Zidane's side closed in on a first La Liga title since 2012, easing to a 4-1 win over Sevilla on Sunday while Neymar hit a hat-trick for Barcelona, who thrashed Las Palmas 4-1.
A late double from Cristiano Ronaldo put some gloss on a stuttering performance from Real Madrid as they beat Celta Vigo 3-0 to cut the gap at the top of La Liga to five points.
Carlos Tevez has been included in the squad for the first time in three years for next month's friendlies in England against Croatia and Portugal.
News of all that's transpired on and off the football field
Fiorentina tore apart Italian rivals AS Roma to reach the Europa League quarter-finals with a 3-0 win that left their opponents' season in tatters and under-fire coach Rudi Garcia tottering on the brink of the sack.
Images from Day 2 of the 2020 US Open in New York
Liverpool had won each of their previous four home leagues games in which they conceded first and 12 minutes later they had turned another match on its head as Roberto Firmino's trickery set up Mane to give the hosts the lead at the second attempt.
It will have made uneasy viewing for coach Jorge Sampaoli and emphasised more than ever how reliant his side are on their talisman Messi, who has been struggling with a muscle problem.
Ruthless Bayern Munich scored five goals in the first 35 minutes on the way to a 7-1 demolition of AS Roma on Tuesday which bore an uncanny resemblance to Germany's win over Brazil by the same score in the World Cup semi-final.
Roberto Firmino's goal gave Brazil a 1-0 victory over Chile in a feisty friendly at the Emirates Stadium in London on Sunday, their eighth successive win since last year's disappointing World Cup campaign.
